DOCTORAL THESES

2023

1. ​Nicola Piasentin (ESR4): Combined Molecular Dynamics and Thermodynamics Modelling of Skin Lipid Bilayer Structure and Barrier Property - Effect of Hydration and Exposure to Chemicals. Doctoral Thesis, University of Surrey (2023). DOI
    

2. Pakhi Chaturvedi (ESR7): Sensorial and Physiological Response in the Skin Device Interaction for Personal Care/Devices. Doctoral Thesis, University of Southampton (2023). PDF
    

3. Nkemjika Abiakam (ESR3): Detecting Early Signs of Skin Damage Using Non-invasive Biophysical Parameters. Doctoral Thesis, University of Southampton (2023). PDF
    

4. Hemalatha Jayabal (ESR2): Identifying Early Changes in Skin Integrity using Biomarkers. Doctoral Thesis, University of Southampton (2023). PDF
    

5. Yisha Chen (ESR13): Portable Instrument to Rapidly Assess Mechanical Properties of the Skin. Doctoral Thesis, Université de Lille (2023). PDF
    

2022

1. Ekaterina Mukhina (ESR9): Experimental and Numerical Approach for the Biomechanical Modeling of the Sacral Soft Tissues in the Context of Pressure Ulcer Prevention. Doctoral Thesis, Université Grenoble Alpes (2022). PDF
    

2. ​Alessio Trebbi (ESR8): Definition of a Methodology to Evaluate Finite Element Models of the Human Heel for the Prevention of Pressure Ulcers. Doctoral Thesis, Université Grenoble Alpes (2022). PDF
   
    

JOURNAL ARTICLES 

CONFERENCE ABSTRACTS & PAPERS
2024

1. The frictional energy absorber effectiveness and its impact on the pressure ulcer prevention performance of multilayer dressings. Cécile Marché, Sue Creehan and Amit Gefen, , Int Wound J 21, e14871 (2024). DOI
    

2023

1. Biophysical and biochemical changes in skin health of healthcare professionals using respirators during COVID-19 pandemic. Nkemjika Abiakam, Hemalatha Jayabal, Kay Mitchell, Dan Bader and Peter Worsley, Skin Res Technol 29, e13239 (2023). DOI  PDF
    

2. A piezoelectric based sensor system designed for in vivo skin biomechanical measurements. Yisha Chen, Betty Lemaire-Semail, Frédéric Giraud and Vincent Hayward, Sensors Actuators A Phys 351, 114168 (2023). DOI
    

3. Characterisation of superficial corneocytes in skin areas of the face exposed to prolonged usage of respirators by healthcare professionals during COVID-19 pandemic. Ana Évora, Nkemjika Abiakam, Hemalatha Jayabal, Peter Worsley, Zhibing Zhang, Simon Johnson, Michael Adams and Dan Bader, J Tissue Viability 32, 305–313 (2023). DOI  PDF
    

4. Inflammatory biomarkers in sebum for identifying skin damage in patients with a Stage I pressure ulcer in the pelvic region: a single centre observational, longitudinal cohort study with elderly patients. Hemalatha Jayabal, Nkemjika Abiakam, Davide Filingeri, Dan Bader and Peter Worsley, Int Wound J 20, 2594–2607 (2023). DOI  PDF
    

5. Development of an efficient extraction methodology to analyse potential inflammatory biomarkers from sebum. Hemalatha Jayabal, Dan Bader and Peter Worsley, Skin Pharmacol Physiol 36, 38–50 (2023). DOI  PDF
    

6. In-silico prediction of stratum corneum partition coefficients via COSMOmic and molecular dynamics simulations. Nicola Piasentin, Guoping Lian and Qiong Cai, J Phys Chem B 127, 2719–2728 (2023). DOI
    

7. Spatial and temporal changes in biophysical skin parameters over a category I pressure ulcer. Nkemjika Abiakam, Hemalatha Jayabal, Davide Filingeri, Dan Bader and Peter Worsley, Int Wound J 20, 3164–3176 (2023). DOI  PDF
    

8. Definition and evaluation of a finite element model of the human heel for diabetic foot ulcer prevention under shearing loads. Alessio Trebbi, Nolwenn Fougeron and Yohan Payan, Med Eng Phys 118, 104022 (2023). DOI
    

9. Design of a low-frequency ultrasound diagnostic sensor based on skin mechanical impedance. Elis Castro, Frédéric Giraud, Betty Lemaire-Semail and Anis Kaci, Sensors Actuators A Phys 358, 114400 (2023). DOI
    

10. Comparing the stiffness of the skin to that of commonly used skin-contacting medical devices in context of MDRPU. Aleksei Orlov, Orel Belo, Susan Solmos, Janet Cuddigan and Amit Gefen, 28th Congress of the European Society of Biomechanics, 9th – 12th July 2023. PDF
     

11. Investigation of gender-specific risks of skin folding after bariatric surgery: a computational approach. Jessica Ralvoni, Frank Baaijens and Sandra Loerakker, 28th Congress of the European Society of Biomechanics, 9th – 12th July 2023. PDF
     

12. Characterisation of superficial corneocyte properties over category I pressure ulcers: insights into topographical and maturation changes. Ana Évora, Nkemjika Abiakam, Zhibing Zhang, Simon Johnson, Michael Adams, Dan Bader and Peter Worsley, J Dermatological Sci 112, 63–70 (2023). DOI   PDF
     

13. Medical device testing: methods, significance, and clinical applications. Susan Solmos, Amit Gefen, Joyce Black, Aleksei Orlov, Orel Belo and Janet Cuddigan, Adv Skin Wound Care 36, 513–522 (2023). DOI   PDF
     

14. An examination of published datasets of skin permeability and partition coefficients. Benjamin Deacon, Nicola Piasentin, Qiong Cai, Tao Chen and Guoping Lian, Toxicology in Vitro 93, 105702 (2023). DOI
     

15. Getting under the skin of a stage I pressure ulcer. Peter Worsley, Silvia Caggiari, Nkemji Abiakam, Hemalatha Jayabal and Ana Evora, EPUAP 2023, Paper 2.1, 13th September 2023. PDF
     

16. Laboratory bioengineering testing to compare the skin stiffness with materials in commonly used skin contacting medical devices as a risk measure for device-related pressure ulcers. Aleksei Orlov, Orel Belo, Susan Solmos, Janet Cuddigan and Amit Gefen, EPUAP 2023, Paper 2.3, 13th September 2023. PDF
     

17. Influence of thermal properties of dressings used for preventing medical device-related pressure ulcers: the case of a continuous positive airway pressure mask. Cecile Marche, Aleksei Orlov and Amit Gefen, EPUAP 2023, Paper 2.4, 13th September 2023. PDF
     

18. Characterisation of topographical, biomechanical and maturation properties of corneocytes with respect to anatomical location. Ana Évora, Zhibing Zhang, Simon Johnson and Michael Adams, Skin Res Technol 29, e13507 (2023). DOI
     

19. The effects of incontinence pad application on loaded skin with reference to biophysical and biochemical parameters: an exploratory cohort study using a repeated measure design. Nkemjika Abiakam, Hemalatha Jayabal, Shabira Abbas, Davide Filingeri, Dan Bader and Peter Worsley, J Wound Ostomy Continence Nurs 50, 512–520 (2023). DOI  PDF
     

20. The effects of hydration on the topographical and mechanical properties of corneocytes. Ana Évora, Zhibing Zhang, Simon Johnson and Michael Adams, J Mech Behav Biomed Mater 150, 106296 (2024). DOI

2022

1. The potential of a canister-based single-use negative pressure wound therapy system delivering a greater and continuous absolute pressure level to facilitate better surgical wound care. Aleksei Orlov and Amit Gefen, Int Wound J 19, 1471–1493 (2022). DOI   PDF
    

2. Reliability of B-mode ultrasound and shear wave elastography in evaluating sacral bone and soft tissue characteristics in young adults with clinical feasibility in elderly. Maher Abou Karam, Ekaterina Mukhina, Nils Daras, Isabelle Rivals, Hélène Pillet, Wafa Skalli, Nathanaël Connesson, Yohan Payan and Pierre-Yves Rohan, J Tissue Viability 31, 245–254 (2022). DOI   PDF
    

3. The fluid handling performance of the curea P1 multipurpose dressing against superabsorbent and foam dressing technologies. Aleksei Orlov and Amit Gefen, Int Wound J 19, 945–956 (2022). DOI
    

4. Fluid handling dynamics and durability of silver-containing gelling fiber dressings tested in a robotic wound system. Aleksei Orlov, Adi Lustig, Angela Grigatti and Amit Gefen, Adv Skin Wound Care 35, 326–334 (2022). DOI
    

5. Tissue internal strains computed by a finite element model of the human heel and measured from MR images. Alessio Trebbi, Mathieu Bailet, Antoine Perrier and Yohan Payan, 27th Congress of the European Society of Biomechanics, 26th - 29th June 2022. PDF
    

6. Effective negative pressure wound therapy for open wounds: The importance of consistent pressure delivery. Aleksei Orlov and Amit Gefen, Int Wound J 20, 328–344 (2023). DOI
    

7. MR-based quantitative measurement of human soft tissue internal strains for pressure ulcer prevention. Alessio Trebbi, Ekaterina Mukhina, Pierre-Yves Rohan, Nathanaël Connesson, Mathieu Bailet, Antoine Perrier and Yohan Payan, Med Eng Physics 108, 103888 (2022). DOI   PDF
    

8. Differences in prophylactic performance across wound dressing types used to protect from device-related pressure ulcers caused by a continuous positive airway pressure mask. Aleksei Orlov and Amit Gefen, Int Wound J 20, 942–960 (2023). DOI
    

9. In vivo quantification of 3D displacement in sacral soft tissues under compression: Relevance of 2D US-based measurements for pressure ulcer risk assessment. Ekaterina Mukhina, Alessio Trebbi, Pierre-Yves Rohan, Nathanaël Connesson and Yohan Payan, J Tissue Viability 31, 593–600 (2022). DOI   PDF
    

10. Fluid handling performance of wound dressings tested in a robotic venous leg ulcer system under compression therapy. Aleksei Orlov and Amit Gefen, Int Wound J 20, 1384–1392 (2023). DOI
     

11. In vivo estimation of skin elasticity: would you choose US Shear Wave Elastography or a custom-made aspiration device? Ekaterina Mukhina, Nathanaël Connesson, Pierre-Yves Rohan and Yohan Payan, Comput Meth Biomech Biomed Eng 25:sup1, S217–S219 (2022). DOI   PDF
     

12. Properties of corneocytes in the context of skin health. Ana Evora, Nkemjika Abiakam, Shabira Abbas, Simon Johnson, Peter Worsley, Michael Adams and Dan Bader, EPUAP 2022 - STINTS Symposium, Paper 10-1, 15th September 2022.  PDF
     

13. An optimised method to analyse inflammatory markers from sebum and its role in detecting skin damage. Hemalatha Jayabal, Nkemjika Abiakam, Peter Worsley and Dan Bader, EPUAP 2022 STINTS Symposium, Paper 10-2, 15th September 2022.  PDF
    Hemalatha Jayabal - EPUAP 2022 Best Student Presentation Award: PDF
     

14. A foam dressing is considerably advantageous over a hydrocolloid for prophylaxis of noninvasive ventilation mask-related pressure ulcers. Aleksei Orlov and Amit Gefen, EPUAP 2022 - STINTS Symposium, Paper 10-3, 15th September 2022.  PDF
     

15. Can non-invasive skin parameters reflect changes at grade 1 pressure ulcer skin sites? Nkemjika Abiakam, Hemalatha Jayabal, Peter Worsley and Dan Bader, EPUAP 2022 - STINTS Symposium, Paper 10-4, 15th September 2022.  PDF
     

16. Low-frequency ultrasound device for pressure ulcer diagnosis. Elis de Castro, Frédéric Giraud and Betty Lemaire-Semail, EPUAP 2022 - STINTS Symposium, Paper 10-5, 15th September 2022.  PDF
     

17. Contribution of the out-of-plane component in the assessment of sacral soft tissue deformations under compressive loading - Preliminary study on one subject. Ekaterina Mukhina, Pierre-Yves Rohan, Nathanael Connesson and Yohan Payan, EPUAP 2022 - STINTS Symposium, Paper 11-1, 15th September 2022.  PDF
     

18. Human heel internal tissue displacements and strains calculated from Magnetic Resonance Imaging. Alessio Trebbi, Bethany Keenan, Mathieu Bailet, Antoine Perrier and Yohan Payan, EPUAP 2022 - STINTS Symposium, Paper 11-2, 15th September 2022.  PDF
     

19. Molecular dynamics simulation and thermodynamical approaches to predict and model the barrier function of skin lipids. Nicola Piasentin, Guoping Lian and Qiong Cai, EPUAP 2022 - STINTS Symposium, Paper 11-3, 15th September 2022.  PDF
     

20. Characterization of skin integrity by quasi-static mechanical impedance device. Yisha Chen, Betty Lemaire-Semail, Frédéric Giraud and Vincent Hayward, EPUAP 2022 - STINTS Symposium, Paper 11-4, 15th September 2022.  PDF
     

21. Development of a finite element model for the heterogeneous structure of the calcaneal fat pad to study its loading distribution. Insights for stress-related injuries. Alessio Trebbi, Antoine Perrier, Mathieu Bailet and Yohan Payan, EPUAP 2022, Paper 12-2, 15th September 2022.  PDF

2021

1. Personal protective equipment related skin reactions in healthcare professionals during COVID-19. Nkemjika Abiakam, Peter Worsley, Hemalatha Jayabal, Kay Mitchell, Michaela Jones, Jacqui Fletcher, Fran Spratt and Dan Bader, Int Wound J 18, 312–322 (2021). DOI   DOC 
   Top Cited Article Int Wound J 2021-22: PDF
    

2. How influential is the stiffness of the foam dressing on soft tissue loads in negative pressure wound therapy? Aleksei Orlov and Amit Gefen, Med Eng Phys 89, 33−41 (2021).  DOI   PDF
    

3. Corneocytes: relationship between structural and biomechanical properties.
   Ana Évora, Mike Adams, Simon Johnson and Zhibing Zhang, Skin Pharmacol Physiol 34, 146–161 (2021).  DOI   PDF
    

4. Anatomical variability of sub-epidermal moisture and its clinical implications. Hemalatha Jayabal, Barbara Bates-Jensen, Nkemjika Abiakam, Peter Worsley and Dan Bader, J Tissue Viability 30, 434–438 (2021). DOI   DOC
    

5. The identification of biophysical parameters which reflect skin status following mechanical and chemical insults. Hemalatha Jayabal, Barbara Bates-Jensen, Nkemjika Abiakam, Peter Worsley and Dan Bader, Clin Physiol Funct Imaging 41, 366–375 (2021). DOI   DOC
    

6. Vector controlled ultrasonic transducer applied to soft material mechanical impedance estimation. Elis Marina Sales de Castro, Frédéric Giraud, Betty Lemaire-Semail and Michel Amberg, ECMSM 2021, 15th IEEE International Workshop of Electronics, Control, Measurement, Signals and their application to Mechatronics (2021). DOI 
    

7. What makes a hydrogel-based dressing advantageous for the prevention of medical device-related pressure ulcers. Angela Grigatti and Amit Gefen, Int Wound J 19, 515–530 (2022).  DOI   PDF
    

8. The biomechanical efficacy of a hydrogel-based dressing in preventing facial medical device-related pressure ulcers. Angela Grigatti and Amit Gefen, Int Wound J 19, 1051–1063 (2022). DOI   PDF
    

9. Quantifying skin sensitivity caused by mechanical insults: A review. Pakhi Chaturvedi, Peter Worsley, Giulia Zanelli and Wilco Kroon, Skin Res Tech 28, 187–199 (2022). DOI
   PDF   
    

10. Identification and control of piezoelectric benders for skin mechanical impedance estimation. Yisha Chen, Michel Amberg, Frédéric Giraud, Vincent Hayward and Betty Lemaire-Semail, EPE'21 ECCE Europe, 23rd European Conference on Power Electronics and Applications (2021). DOI   PDF
     

11. MR-compatible loading device for assessment of heel pad internal tissue displacements under shearing load. Alessio Trebbi, Antoine Perrier, Mathieu Bailet and Yohan Payan, Med Eng Phys 98, 125−132 (2021). DOI   PDF
     

12. Evaluation of constrained and restrained molecular dynamics simulation methods for predicting skin lipid permeability. Nicola Piasentin, Guoping Lian and Qiong Cai, ACS Omega 6, 35363−35374 (2021). DOI   PDF
     

13. Silver-containing gelling fibre primary dressings: fluid handling (sorptivity) and durability performances tested on a robotic wound system. Aleksei Orlov, Adi Lustig, Angela Grigatti and Amit Gefen, EPUAP 2021 Virtual Meeting - STINTS Symposium, Paper STINTS1, 18th October 2021. PDF
     

14. Strain calculation from MRI image registration: an application for pressure ulcer prevention. Alessio Trebbi, Yohan Payan, Mathieu Bailet and Antoine Perrier, EPUAP 2021 Virtual Meeting - STINTS Symposium, Paper STINTS2, 18th October 2021. PDF
     

15. What makes a hydrogel-based dressing advantageous for the prevention of medical device-related pressure ulcers. Angela Grigatti and Amit Gefen, EPUAP 2021 Virtual Meeting - STINTS Symposium, Paper STINTS3, 18th October 2021. PDF
     

16. Computational modeling of saggy skin: the effect of skin properties on skin folding formation. Jessica Ralvoni, Frank PT Baaijens and Sandra Loerakker, EPUAP 2021 Virtual Meeting - STINTS Symposium, Paper STINTS4, 18th October 2021. PDF
     

17. In vivo experimental characterization of the biomechanical response of sacral soft tissues under compression using both b-mode ultrasound and MRI: preliminary assessment on 2 healthy volunteers. Ekaterina Mukhina, Pierre-Yves Rohan, Nathanael Connesson and Yohan Payan, EPUAP 2021 Virtual Meeting - STINTS Symposium, Paper STINTS5, 18th October 2021. PDF
     

18. Towards ultrasound based mechanical characterization of skin and skin diseases. Zülal Kizilaslan, Marcel Rutten and Richard Lopata, EPUAP 2021 Virtual Meeting - STINTS Symposium, Paper STINTS6, 18th October 2021. PDF
     

19. Portable probe to rapidly assess mechanical and sensorial properties of skin. Yisha Chen, Betty Lemaire-Semail, Frédéric Giraud, Michel Amberg and Vincent Hayward, EPUAP 2021 Virtual Meeting - STINTS Symposium, Paper STINTS7, 18th October 2021. PDF
     

20. The effects of perceived skin sensitivity on the physiological response to mechanical loading. Pakhi Chaturvedi, Peter Worsley, Wilco Kroon, Dan Bader and Giulia Zanelli, EPUAP 2021 Virtual Meeting - STINTS Symposium, Paper STINTS8, 18th October 2021. PDF
     

21. Molecular dynamics approach to investigate the role of hydration and other surfactants on the geometrical and barrier properties of stratum corneum. Nicola Piasentin, Qiong Cai and Guoping Lian, EPUAP 2021 Virtual Meeting - STINTS Symposium, Paper STINTS9, 18th October 2021. PDF
     

22. Low frequency ultrasound diagnostics sensor for pressure ulcers. Elis de Castro, Betty Lemaire-Semail, Frédéric Giraud and Michel Amberg, EPUAP 2021 Virtual Meeting - STINTS Symposium, Paper STINTS10, 18th October 2021. PDF
     

23. Biomechanical and topographical characterization of corneocytes using AFM with respect to anatomical location. Ana Evora, Simon Johnson, Zhibing Zhang and Michael Adams, EPUAP 2021 Virtual Meeting - STINTS Symposium, Paper SPS1.1, 18th October 2021. PDF
     

24. Detecting the signs of skin damage using biophysical and biomarker approaches. Nkemjika Abiakam, Hemalatha Jayabal, Peter Worsley and Dan Bader, EPUAP 2021 Virtual Meeting - STINTS Symposium, Paper SPS1.2, 18th October 2021. PDF
    Nkemjika Abiakam - EPUAP 2021 Best Student Presentation Award: PDF
     

25. Evaluating the implications of ph substrate and moisture-insulted skin using two different incontinence products. Nkemjika Abiakam, Hemalatha Jayabal, Shabira Abbas, Peter Worsley and Dan Bader, EPUAP 2021 Virtual Meeting - STINTS Symposium, Poster PS1.1, 18th October 2021. PDF
     

26. The influence of gender and ethnicity on facemasks and respiratory protective equipment fit: a systematic review and meta-analysis. Jagrati Chopra, Nkemjika Abiakam, Hansung Kim, Cheryl Metcalf, Peter Worsley and Ying Cheong, BMJ Global Health 6, e005537 (2021). DOI

2020

1. A novel system for dynamic stretching of cell cultures reveals the mechanobiology for delivering better negative pressure wound therapy. Rona Katzengold, Alexey Orlov and Amit Gefen, Biomech Model Mechanobiol 20, 193–204 (2021).  DOI   PDF
    

2. Feasibility of using 2D ultrasound data for building a personalized numerical model of the sacral region for the evaluation of the subject-specific risk of sacral pressure ulcer. Ekaterina Mukhina, Pierre-Yves Rohan, Nathanael Connesson and Yohan Payan. EPUAP Virtual Meeting 2020, Paper 5B-2, 24th September 2020.  DOI   PDF
    

3. Development of a finite element model for the heterogeneous structure of the calcaneal fat pad to study its loading distribution. Insights for stress-related injuries. Alessio Trebbi, Antoine Perrier, Mathieu Bailet and Yohan Payan. EPUAP Virtual Meeting 2020, Paper 5B-6, 24th September 2020.  DOI   PDF
    

4. An integrated modelling framework for optimizing negative pressure wound therapy. Aleksei Orlov, Rona Greifman and Amit Gefen. EPUAP Virtual Meeting 2020, Paper 3B-2, 24th September 2020.  DOI   PDF
    

5. PPE related skin reactions in healthcare professionals during COVID19. Nkemjika Abiakam, Peter Worsley, Hemalatha Jayabal and Dan Bader. EPUAP Virtual Meeting 2020, Paper 5C-13, 24th September 2020.  DOI   PDF
    

6. Calibration of the fat and muscle hyperelastic material parameters for the assessment of the internal tissue deformation in relation to pressure ulcer prevention. Ekaterina Mukhina, Pierre-Yves Rohan, Nathanael Connesson and Yohan Payan, Comput Meth Biomech Biomed Eng 23:sup1, S197–S199 (2020).  DOI   PDF
    

7. A 3D registration methodology to evaluate the goodness of fit at the individual-respiratory mask interface. Jeroen Verberne, Peter Worsley and Dan Bader, Comput Meth Biomech Biomed Eng 24, 728–739 (2021).  DOI   DOC
   
    

2019

1. Bioengineering considerations in the prevention of medical device-related pressure ulcers. Dan Bader, Peter Worsley and Amit Gefen, Clin Biomech 67, 70−77 (2019). DOI   DOC